Azabicyclo quinolone carboxylic acids

Details Azabicyclo quinolone carboxylic acids Azabicyclo quinolone carboxylic acids

C - Chemistry, Metallurgy

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C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/635 (2006.01) C07D 209/52 (2006.01) C07D 215/56 (2006.01) C07D 401/04 (2006.01) C07D 498/06 (2006.01)

Patent

CA 2023217

Quinolone carboxylic acids 7-substituted by azabicyclo groups of the formula: Image (wherein R1 is H, cation or alkyl, Y is alkyl, vinyl, cycloalkyl or fluorophenyl, W is H, halogen, alkyl, alkoxy, amino or aminomethyl, A is CH, CF, CC?, COCH3, CCH3, CCN, or N, or A is carbon and taken together with Y and the carbon and nitrogen to which A and Y are attached to form a 5- or 6-membered ring and /R2 is Image or Image wherein R3, R4, R5, R6, R7, R10 and R25 are H or (aminated)methyl; R5, R6, R7 and R9 may be (alkyl)amino) have antibacterial activity.

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