Azabicylic compounds, methods, and intermediates

Details Azabicylic compounds, methods, and intermediates Azabicylic compounds, methods, and intermediates

C - Chemistry, Metallurgy

07

D

260/248.6

C07D 487/18 (2006.01)

Patent

CA 1082188

Abstract of the Disclosure Azabicyclic compounds are disclosed having the formula: Image wherein: A is a member selected from the group consisting of Image and Image ; R1 is a member selected from the group consisting of loweralkyl, phenyl, substituted phenyl, phenyl lower alkyl, substituted phenyl lower alkyl, loweralkylamido phenyl, and heterocyclic aryl selected from pyridyl, quinolyl, imidazolyl, pyrazinyl, pyrrolyl, thienyl, thiazolyl, oxazolyl and pyrimidinyl; R3 and R4 are each members selected from the group consisting of hydrogen or loweralkyl; R6 is a member selected from the group consisting of loweralkyl, phenyl, and substituted phenyl; and R7 and R8 are each members selected from the group consisting of hydrogen, halo, loweralkyl, loweralkoxy, and amino. These azabicyclic compounds are useful for their central nervous system depressant and cardiovascular activity.

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