Azacyclic spiroderivatives as hsl inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2760340

Compounds of formula (I) as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein n, m, A, R1 and R2 have the significance given in claim 1. The compounds are useful as HSL inhibitors for the treatment of diabetes dyslipidemia, atherosclerosis and obesity.

La présente invention a pour objet des composés de formule (I) ainsi que des sels pharmaceutiquement acceptables de ceux-ci pouvant être utilisés sous la forme de compositions pharmaceutiques, n, m, A, R1 et R2 ayant la signification donnée dans la revendication 1. Les composés sont utiles en tant qu'inhibiteurs de la HSL pour le traitement du diabète, de la dyslipidémie, de l'athérosclérose et de l'obésité.

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