Azacyclooctadiene compound and pharmaceutical use

Details Azacyclooctadiene compound and pharmaceutical use Azacyclooctadiene compound and pharmaceutical use

C - Chemistry, Metallurgy

07

D

167/209, 167/233

C07D 405/10 (2006.01) C07D 317/58 (2006.01) C07D 317/60 (2006.01) C07D 405/06 (2006.01) C07D 413/06 (2006.01) C07D 491/04 (2006.01) C07D 491/14 (2006.01) C07D 491/147 (2006.01) C07D 498/14 (2006.01)

Patent

CA 2010742

Abstract An azacyclooctadiene compound having the formula (1) or a pharmacologically acceptable salt thereof is novel and useful as an anti-tumor agent. Image (1) in which R1 is -CH2R, R being hydrogen, -COCH3, -OH, -NH2, -COOH or -OCOCH3, or may form -CH2-X-Y- together with R2; R2 is hydrogen, an alkyl having 1 to 4 carbon atoms or -COR10, R10 being hydrogen, an alkyl having 1 to 4 carbon atoms, -OR11 or -NHR11, R11 being an alkyl having 1 to 4 carbon atoms, or may form -CH2-X-Y- together with R1; R3, R4 and R5 each are hydrogen or methyl; R6 and R7 each are hydrogen or may form the direct bond to each other; R8 is hydrogen or may form the direct bond to R7; and R9 is hydrogen, -N3, -NH2, -OCH3 or =O; X being oxygen or -NZ-, Z being hydrogen, methyl; -COCH3, -CH2COOH, -CO-CH=CH2, -CO-CH=CH-CH3, -CH2C6H5, -CH2OH, -CH2OCOCH3 or -CH2-COOC(CH3)3, Y being -CS-, -CO- or -CH2-.

Affiliated with

Also associated with

Rating

Azacyclooctadiene compound and pharmaceutical use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Azacyclooctadiene compound and pharmaceutical use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azacyclooctadiene compound and pharmaceutical use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1822849