Azaindole derivatives as inhibitors of p38 kinase

Details Azaindole derivatives as inhibitors of p38 kinase Azaindole derivatives as inhibitors of p38 kinase

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 39/395 (2006.01) A61K 45/06 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2501947

The invention is directed to methods to inhibit p38 kinase, preferably p38- .alpha. using compounds which are azaindoles wherein the azaindoles are coupled through a piperidine or piperazine type linker to another cyclic moiety.

L'invention concerne des méthodes d'inhibition de la kinase P38, de préférence de l'.alpha.-p38, au moyen de composés qui sont des azaindoles. Les azaindoles sont couplés par un lieur du type pipéridine ou pipérazine à un autre fragment cyclique.

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