Azaindole derivatives for the treatment of depression

Details Azaindole derivatives for the treatment of depression Azaindole derivatives for the treatment of depression

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 25/24 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01)

Patent

CA 2367681

Compounds useful in the treatment of diseases affected by disorders of the serotonin-affected neurological systems, such as depression and anxiety, are provided having formula (I) wherein: R1 and R2 form a carbocyclic or heterocyclic ring of 5 to 7 atoms, wherein said ring may be saturated or unsaturated; and X is independently hydrogen, cyano, carbamoyl, halogen or alkoxy; or pharmaceutically acceptable salts thereof.

L'invention concerne des composés utilisés dans le traitement de maladies en rapport avec les troubles des systèmes neurologiques liés à la sérotonine, tel que la dépression et l'anxiété. Ces composés sont représentés par la formule (I), dans laquelle R¿1? et R¿2? forment un noyau carbocyclique ou hétérocyclique de 5 à 7 atomes, ledit noyau pouvant être saturé ou non saturé ; X est indépendamment hydrogène, cyano, carbamoyl, halogène ou alcoxy, ou des sels pharmaceutiquement acceptables desdits composés.

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