C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2234567
Disclosed are compounds that are useful in the treatment of conditions associated with depletion of nicotine receptors in mammals, the compounds having formula I: Image (wherein X is; a) -CH2NR1R2; b) Image ; or c) Image ; where R, R1, and R2 are independently selected from hydrogen and C1-C6 alkyl; R3 is selected from hydrogen, halogen and C1-C6 alkyl; 1 is an integer from 0-4; m is in integer from 0-4; and n is an integer from 0-2); or pharmaceutically acceptable salts thereof.
L'invention porte sur des composés utiles pour le traitement de troubles liés à la déplétion en récepteurs de nicotine chez les mammifères, composés de formule I Image , où : X est a) -CH2NR1R2, b) Image ou c) Image ; R, R1, et R2 sont indépendamment choisis parmi l'hydrogène et un alkyle C1-C6; R3 est choisi parmi un hydrogène, un halogène et un alkyle C1-C6; 1 est un entier de 0 à 4; m est un entier de 0 à 4; enfin, n est un entier de 0 à 2. Elle porte également sur leurs sels de qualité pharmaceutique.
Pfizer Inc.
Smart & Biggar
LandOfFree
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