Azaindole inhibitors of iap

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/04 (2006.01) A61K 31/33 (2006.01) A61P 35/00 (2006.01) C07D 413/02 (2006.01) C07D 413/04 (2006.01) C07D 417/02 (2006.01) C07D 487/02 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2730357

The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula I: I wherein X1, X2, Y, Z1, Z2, Z3, Z4, R1, R2, R3, R3', R4, R4', R5, R6, R6' and R9 are as described herein.

L'invention porte sur de nouveaux inhibiteurs dIAP qui sont utiles en tant qu'agents thérapeutiques pour traiter des tumeurs malignes, les composés ayant la formule générale I : I formule dans laquelle X1, X2, Y, Z1, Z2, Z3, Z4, R1, R2, R3, R3', R4, R4', R5, R6, R6' et R9 sont tels que décrits ici.

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