C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01)
Patent
CA 2089470
New azaindoles, preparation processes and medicinal products containing them ABSTRACT These compounds correspond to the formula Image in which one of the groups X1 to X4 represents nitrogen and the others a CH radical, R1 and R2 represent H, halogen, alkyl, hydroxymethyl, alkyloxymethyl, dialkylaminoalkyl, dialkylaminoalkyloxy- methyl, carboxyl, ethyl carboxylate, piperidino, alkenyl, cycloalkyl, cycloalkenyl, alkylthio, benzyl, phenyl, thiophene or pyridine, optionally substituted, R3 and R4 represent H, halogen, alkyl, cycloalkyl, alkoxy or alkylthio, R5 and R6 denote H, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl or alkylthioalkyl, or together form alkylene or alkyleneoxyalkylene chains, R7 denotes H, alkyl or cycloalkyl; one of the radi- cals R5 to R7 can also denote optionally substituted phenyl or benzyl, R8 represents H, alkyl, cycloalkyl or optionally substituted phenyl or benzyl, R9 denotes optionally substituted phenyl, naphthyl or heterocyclic, as well as their tautomeric forms, processes for preparing them and application as hypolipidaemic and antiatheromatous medicinal products.
Decerprit Jacques
Descours Denis
Festal Didier
Lipha Lyonnaise Industrielle Pharmaceutique
Swabey Ogilvy Renault
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