Azanaphthaleneacetic acid derivative

Details Azanaphthaleneacetic acid derivative Azanaphthaleneacetic acid derivative

C - Chemistry, Metallurgy

07

D

260/289

C07D 215/22 (2006.01) C07D 215/227 (2006.01) C07D 217/24 (2006.01)

Patent

CA 1082711

ABSTRACT OF THE DISCLOSURE Azanaphthaleneacetic acid derivatives having anti-inflammatory activity are described herein. The subject compounds can be prepared by reacting the appropriate alkyl 8-hydroxy-3-alkoxy-5,6,7,8-tetrahydro- 2-azanaphthalene-7-methylidene-carboxylate with a metallic salt of a secondary organic base and further reacting this reaction mixture with acetic acid to give the simple acetic acid derivatives or methyl iodide when the .alpha.-alkylated products are desired.

257037

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