Azasteroid compounds for the treatment of prostatic...

Details Azasteroid compounds for the treatment of prostatic... Azasteroid compounds for the treatment of prostatic...

C - Chemistry, Metallurgy

07

J

C07J 73/00 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2054368

Compounds of formula (I): (see formula I) (in which: R1 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or a heterocyclic-substituted alkyl group; R2 is an aryl-substituted alkyl group, a heterocyclic-substituted alkyl group or a diarylamino group; R3 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or an alkenyl group having from 3 to 6 carbon atoms; and each of the bonds represented by .alpha.-.beta. and .gamma.-.delta. is a carbon-carbon single bond or a carbon-carbon double bond;) and pharmaceutically acceptable salts and esters thereof are useful for the treatment and prophylaxis of prostatic hypertrophy. We also provide processes for their preparation.

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