Azepine or larger medium ring derivatives and their use as...

Details Azepine or larger medium ring derivatives and their use as... Azepine or larger medium ring derivatives and their use as...

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/55 (2006.01) C07D 223/06 (2006.01) C07D 223/08 (2006.01) C07D 223/12 (2006.01) C07D 225/02 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2314154

Selected novel azepine and larger medium ring compounds of the formula (see formula I) are effective for prophylaxis and treatment of inflammation, tissue degradation and related diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of inflammation, tissue degradation and related diseases. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

L'invention porte sur de nouveaux composés azépine qui sont efficaces dans la prophylaxie et le traitement des inflammations, de la dégradation tissulaire et de maladies apparentées. Cette invention porte sur de nouveaux composés, des analogues, des promédicaments et leurs sels pharmaceutiquement acceptables, sur des compositions pharmaceutiques et des procédés utiles à la prophylaxie et au traitement des inflammations, de la dégradation tissulaire et de maladies apparentées. L'invention porte également sur des procédés de fabrication de ces composés, ainsi que sur leurs intermédiaires utilisés dans ces procédés.

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