Azepinoindole and pyridoindole derivatives as pharmaceutical...

Details Azepinoindole and pyridoindole derivatives as pharmaceutical... Azepinoindole and pyridoindole derivatives as pharmaceutical...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 223/00 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2485909

The present invention is directed to compounds of formula (I) and formula (II): formula (I) and (II), wherein R1-R8, A and n are as described in the description. These compounds are used in pharmaceutical compositions and methods for modulating the activity of orphan nuclear receptors.

Cette invention concerne des composés à utiliser dans des compositions pharmaceutiques et des méthodes permettant de moduler l'activité de récepteurs nucléaires. L'invention concerne en particulier des compositions et des méthodes de modulation du récepteur farnesoïde X et/ou de récepteurs nucléaires orphelins. Ces composés sont représentés par les formules (I) (II), dans lesquelles R?1¿-R?8¿, A et n sont comme définis dans le descriptif.

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