Azepinone compounds useful in the inhibition of ace and nep

Details Azepinone compounds useful in the inhibition of ace and nep Azepinone compounds useful in the inhibition of ace and nep

C - Chemistry, Metallurgy

07

D

C07D 223/10 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01) C07D 223/32 (2006.01) C07D 401/00 (2006.01) C07D 403/04 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 417/00 (2006.01) C07F 9/553 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2168303

Compounds having the following formulae I and II, and pharmaceutically acceptable salts thereof, including dual inhibitors of ACE and NEP and selective ACE inhibitors: (I) Image Image (II) wherein: Image , Image , A is Image , or Image ; and wherein R, R1, R2, R3, R4, R5, R5a, R5b, R6, R7, R11, q and r are defined herein.

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