Azetidin-2-on derivatives and process for production thereof

C - Chemistry – Metallurgy – 07 – D

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260/310.1, 260/3

C07D 277/16 (2006.01) C07D 205/08 (2006.01) C07D 417/06 (2006.01) C07D 498/04 (2006.01)

Patent

CA 1282415

Abstract of the Disclosure An azetidin-2-one derivative represented by the following formula (I) Image (I) wherein R1 represents a hydroqen atom, a lower alkyl group, an aryl grouo, an aralkyl group, a lower alkoxy group, aralkoxy group, a lower alkylthio group, an aralkyl- thio group, or a substituted amino group, R2 represents a hydrogen atom, a lower alkyl group, an aryl group or an aralkyl group, and R3 represents a hydrogen atom or a group of the formula Image in which R4 represents a hydrogen atom or a protective group for the hydroxyl group; and a process for production thereof. The novel derivatives are useful as intermediates for the production of carbapenem-series antibiotics and monocyclis beta-lactam antibiotics.

517002

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