C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61K 31/444 (2006.01) A61P 3/06 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) C07D 487/10 (2006.01)
Patent
CA 2663947
Disclosed are compounds of formula (I) wherein Z1 is -CH2- or -C(O)-, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5, and R2 is heteroaryl, and R1 and R3 are as defined herein. Also disclosed are methods of treating pain using a compound of formula (I).
L'invention concerne des composés représentés par la formule (1) dans laquelle Z1 est -CH2- ou -C(O)-, R4 et R5 sont des chaînes de carbone ( et éventuellement, ils forment ensemble un pont en C2) u et v sont indépendamment un entier compris entre 0 et 3 de sorte que leur somme soit comprise entre 3 et 5, et R2 est hétéroaryle, et R1 et R3 sont tels que définis dans les spécifications. L'invention concerne aussi des procédés de traitement de la douleur au moyen des composés représentés par la formule (1).
Bennett Chad E.
Burnett Duane A.
Knutson Chad E.
Mckittrick Brian
Smith Elizabeth M.
Bennett Chad E.
Burnett Duane A.
Knutson Chad E.
Mckittrick Brian
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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