Azetidine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/335.5

C07D 205/08 (2006.01) C07F 9/40 (2006.01) C07F 9/535 (2006.01)

Patent

CA 1129871

ABSTRACT OF THE DISCLOSURE Azetidine derivatives of the formula: Image wherein A is amino or substituted amino; COB is carboxy or protected carboxy; R1 is =C(CH3)2, Image , =PR43 or Image R4 is alkyl, aryl or aralkyl; OR2 and OR3 independently or taken together with each other represent a ketal; Y is hydrogen or methoxy; Z is hydrogen or halogen and a process for preparation thereof. Used as intermediates in the preparation of potent antimicrobials 1-oxadethiacephalosporins.

393848

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