Azetidine derivatives as ccr-3 receptor antagonists

Details Azetidine derivatives as ccr-3 receptor antagonists Azetidine derivatives as ccr-3 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 205/04 (2006.01) A61K 31/395 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2479266

Compounds of formula (I) in free or salt form, wherein Ar, X, Y, R1, R2, R3, R5, m, n, p, and q have the meanings as indicated in the specification, are useful for treating conditions mediated by CCR3. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

L'invention a trait à des composés représentés par la formule (I), sous forme libre ou sous forme de sel, où Ar, X, Y, R?1¿, R?2¿, R?3¿, R?5¿, m, n, p, et q sont tels que définis dans le descriptif. Lesdits composés sont utiles au traitement d'états pathologiques induits par CCR3. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés, et des procédés de préparation desdits composés.

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