Azetidine derivatives as g-protein coupled receptor (gpr119...

C - Chemistry – Metallurgy – 07 – D

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C07D 205/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61P 3/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2648687

Compounds of formula (I) or pharmaceutically acceptable salts thereof, are agonists of GPR119 and are useful for the treatment of diabetes and as peripheral regulators of satiety, e.g. for the treatment of obesity and metabolic syndrome.

La présente invention concerne des composés répondant à la formule (I), ou des sels pharmaceutiquement acceptables desdits composés, qui sont des agonistes du GPR119 et sont utiles pour le traitement du diabète. Les composés sont également utiles en tant que régulateurs périphériques de la satiété, par exemple pour le traitement de l'obésité et du syndrome métabolique.

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