Azetidine derivatives as glyt1 inhibitors

Details Azetidine derivatives as glyt1 inhibitors Azetidine derivatives as glyt1 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/24 (2006.01) A61K 31/44 (2006.01) A61P 25/00 (2006.01) C07C 13/00 (2006.01) C07D 205/04 (2006.01) C07D 231/24 (2006.01) C07D 239/30 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2630039

The present invention relates to compounds of formula (I); and pharmaceutically acceptable salts thereof and individual enantiomers and diastereomers thereof, as GIyTl inhibitors for treating neurological and psychiatric disorders.

La présente invention concerne des composés de formule I : ,R5 R1 N Il > ^\C / A^ R2 \ / N (A)n, v H / / \ Rb « T Ra ^SO2R3 (I) ainsi que des sels de qualité pharmaceutique desdits composés et des énantiomères et des diastéréoisomères purs desdits composés, en tant qu'inhibiteurs de GlyT1, pour le traitement de troubles neurologiques et psychiatriques.

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