Azetidine glycine transporter inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 205/04 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 413/04 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2564501

The present invention is directed to azetidine compounds that inhibit the glycine transporter GlyT1 and which are useful in the treatment of neurological and psychiatric disorders associated with glycinergic or glutamatergic neurotransmission dysfunction and diseases in which the glycine transporter GlyT1 is involved.

La présente invention concerne des composés d'azétidine qui inhibent le transporteur de glycine GlyT1 et lesquels sont utiles dans le traitement de troubles neurologiques et psychiatriques associés à un dysfonctionnement de la neurotransmission glycinergique ou glutamatergique et de maladies dans lesquelles le transporteur de glycine GlyT1 est impliqué.

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