Azetidines as histamine h3 receptor antagonists

Details Azetidines as histamine h3 receptor antagonists Azetidines as histamine h3 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/551 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2751239

The invention relates to compounds of formula (I), wherein R, R1, m, n and X1to X3 have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.

La présente invention porte sur des composés de formule (I), dans laquelle R, R1, m, n et X1 à X3 ont la signification telle que donnée dans la description et les revendications. Lesdits composés sont utiles en tant qu'antagonistes des récepteurs H3 de l'histamine. L'invention porte également sur des compositions pharmaceutiques, sur la préparation de tels composés ainsi que sur la production d'un médicament et sur leur utilisation en tant que médicament.

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