C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/42 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61P 35/00 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 239/28 (2006.01) C07D 241/24 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2570169
The invention relates to chemical compounds, of the formula (I): or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
L'invention se réfère á des composés chimiques de la formule (I): ou des sels pharmaceutiquement acceptables qui possèdent l'activité inhibitrice B-Raf et sont par conséquent utiles pour leur activité anti-cancéreuse et sont ainsi utilisés dans des procédés de traitement de corps humain ou animaux. L'invention se réfère également á la fabrication de composés chimiques, de compositions pharmaceutiques les contenant et à leur utilisation dans la fabrication de médicaments pour produire un effet anticancéreux dans un animal à sang chaud tel que l'être humain.
Aquila Brian
Ioannidis Stephanos
Lyne Paul
Pontz Timothy
Astrazeneca Ab
Fetherstonhaugh & Co.
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