Azlactone graft copolymers

Details Azlactone graft copolymers Azlactone graft copolymers

C - Chemistry, Metallurgy

08

F

400/2048, 400/30

C08F 255/00 (2006.01) C08L 51/06 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2014156

Abstract of the Disclosure Graft copolymers and processes for the ??eparation thereof are provided. The copolymers comprise a base polymer having grafted thereto a monomeric 2-alkenyl azlactone. The surface properties of the graft copolymers can be modified by binding thereto nucleophilic reagents comprising further functional groups with desired properties. Further, the amount of azlactone available at the surface of a graft copolymer for binding to such nucleophilic reagents can be controlled by selecting a surface against which the graft copolymer is formed. The graft copolymers exhibit desirable thermoplastic, melt flow, and adhesion properties and are particularly useful for immobilizing proteins. Methods of immunoassay based on the immobilization of proteins are also disclosed. Another utility of the graft copolymers involves the compatibilizing of immiscible polymer blends.

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