Azole compounds as anti-fungals agents

A - Human Necessities – 61 – K

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A61K 31/41 (2006.01) C07D 249/12 (2006.01)

Patent

CA 2433259

The present invention relates to the derivatives of specially substituted azole compounds which have improved antifungal activity as compared with presently available agents in this class and the processes for the preparation thereof. This invention also relates to pharmaceutical preparations containing the compounds of the present invention and their use in treating and/or preventing the fungal infections in mammals, preferably humans.

La présente invention concerne des dérivés de composés azoliques spécialement substitués présentant une activité antifongique améliorée par comparaison avec des agents actuellement disponibles dans cette classe, ainsi que leurs procédés de préparation. Cette invention concerne en outre des préparations pharmaceutiques contenant les composé susmentionnés, ainsi que leur utilisation dans le traitement et/ou la prévention d'infections fongiques chez des mammifères, et notamment chez l'homme.

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