C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 521/00 (2006.01) A61K 31/41 (2006.01) C07D 249/12 (2006.01)
Patent
CA 2402345
The present invention relates to the derivatives of specially substituted azole compounds which have improved antifungal activity as compared to known compounds such as fluconazole and itraconazole and the processes for the preparation thereof. This invention also relates to pharmaceutical compositions containing the compounds of the present invention and their use in treating and/or preventing fungal infections in mammals, preferably humans.
L'invention concerne des dérivés de composés azole substitués de manière spéciale qui possèdent une activité antimycosique accrue par comparaison avec des composés connus tels que le fluconazole et l'itraconazole, ainsi que des procédés de préparation de ces dérivés. L'invention concerne aussi des compositions pharmaceutiques contenant ces composés, et leur utilisation pour traiter et/ou prévenir des infections mycosiques chez des mammifères, de préférence des êtres humains.
Arora Jasbir Singh
Arora Sudershan K.
Rattan Ashok
Verma Ashwani Kumar
Ranbaxy Laboratories Limited
Ridout & Maybee Llp
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