Azole compounds, their production and their use

Details Azole compounds, their production and their use Azole compounds, their production and their use

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) A01N 43/653 (2006.01) A01N 43/713 (2006.01) A61K 31/41 (2006.01) C07D 249/08 (2006.01) C07D 403/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2281875

A quaternized nitrogen-containing imidazol-1-yl or 1,2,4-triazol-1-yl compound wherein one of nitrogen atoms constituting an azole ring is quaternized with a substituent capable of being eliminated in vivo and the substituent can be eliminated in vivo to be converted into an antifungal azole compound, have an improved solubility in water, can advantageously be applied to injection, have an improved internal absorption and can be expected to have a good effect for the treatment or prevention of disease.

L'invention concerne un composé d'imidazol-1-yl ou 1,2,4-triazol-1-yl contenant du nitrogène et quaternarisé, dans lequel un des atomes de nitrogène constituant un noyau d'azole est quaternarisé avec un substituant capable d'être éliminé in vivo, le substituant pouvant être éliminé in vivo de manière à être transformé en un composé de type azole antifongique; ce composé possède une solubilité améliorée dans l'eau, peut être appliqué de manière avantageuse par injection, possède une capacité améliorée d'absorption interne et est capable de présenter un effet bénéfique dans le traitement ou la prévention d'affections.

Affiliated with

Also associated with

Rating

Azole compounds, their production and their use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Azole compounds, their production and their use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azole compounds, their production and their use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2057744