Azole compounds, their production and use

Details Azole compounds, their production and use Azole compounds, their production and use

C - Chemistry, Metallurgy

07

D

C07D 249/08 (2006.01) A01N 43/50 (2006.01) A01N 43/653 (2006.01) A01N 43/72 (2006.01) A01N 43/78 (2006.01) A01N 43/80 (2006.01) A01N 43/82 (2006.01) A01N 47/16 (2006.01) C07D 233/61 (2006.01) C07D 401/00 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2067272

ABSTRACT OF THE DISCLOSURE An azole compound represented by the formula (I): Image (I) wherein X is a nitrogen atom or CH; Ar is a substituted phenyl group; R1 and R2 independently are a hydrogen atom or a lower alkyl group, or they may combine together to form a lower alkylene group; B is a group of the formula: Image (wherein R3 and R4 independently are a hydrogen atom, an optionally substituted aliphatic or aromatic hydrocarbon residue or an optionally substituted heterocyclic group, or they may form an optionally substituted heterocyclic group together with the nitrogen atom to which they are bonded; and n denotes an integer of 0 to 2), or a group of the formula: Image (wherein R5 and R6 independently are a hydrogen atom, an optionally substituted aliphatic or aromatic hydrocarbon residue group or an optionally substituted heterocyclic group, or they may form an optionally substituted heterocyclic group together with the nitrogen atom and sulfur atom to which they are bonded; and m denotes an integer of 0 to 2); and R7 is a hydrogen atom or an acylated hydroxyl group, or may form a bond together with R1, or a salt thereof, which is useful as an antifungal agent.

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