Azole derivatives, process for their preparation, and their use

C - Chemistry – Metallurgy – 07 – D

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C07D 233/66 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 233/68 (2006.01) C07D 233/70 (2006.01) C07D 233/90 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 453/02 (2006.01) C07D 521/00 (2006.01) C07F 9/6506 (2006.01)

Patent

CA 2058198

HOE 91/F 001 K ABSTRACT OF THE DISCLOSURE Azole derivatives, process for their preparation, and their use Azole derivatives of the formula (I) (I) Image in which A, L, O, R1, X, Y, Z and q have the meanings given, process for their preparation, pharmaceutical preparations and the use of the compounds are described. Azole derivatives of the formula I where the symbols have for example the following meanings: R1 is (C2-C10)-alkyl, Z is nitrogen, X and Y are independently of one another CR2, L is -CH2-, q is zero or 1, A is a biphenyl radical which is substituted for example by R15 R2 is halogen or hydrogen R15 is SO2-NH-CO-OR6 and R6 is phenyl, are highly active antagonists of angiotensin II recep- tors.

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