Azole derivatives, their use, production and usage

Details Azole derivatives, their use, production and usage Azole derivatives, their use, production and usage

C - Chemistry, Metallurgy

07

D

C07D 277/48 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) A61K 31/695 (2006.01) C07D 233/88 (2006.01) C07D 263/48 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2185082

The present invention relates to an azole derivative represented by the general formula (I): Image (I) [wherein each of R1, R2 and R3 is H, halogen, C1-8alkyl or the like, and A is a group represented by the formula (i) or (ii): Image Image (i) (ii) (wherein R4, R5, R6 and X are as defined in the specification.)] and a pharmacologically acceptable salt thereof, which have ACAT-inhibitory activity and are useful as a prophylactic and therapeutic agent for hypercholesterolemia, atherosclerosis and various diseases caused by them; a process for producing said derivative; and an ACAT inhibitor containing said derivative or salt as an active ingredient.

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