Azolidinone-vinyl fused-benzene derivatives

Details Azolidinone-vinyl fused-benzene derivatives Azolidinone-vinyl fused-benzene derivatives

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/00 (2006.01) A61P 37/06 (2006.01) C07D 277/18 (2006.01) C07D 277/20 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2493843

The present invention is related to azolidinedione-vinyl fused-benzene derivatives of formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, graft rejection or lung injuries. Formula (I), wherein A, X, Y, Z, R1 , R2 and n are as described in the description.

L'invention concerne des dérivés de benzène à fusion azolidinone-vinyle de formule (I), pour le traitement et/ou la prévention des maladies auto-immunes et/ou inflammatoires, cardio-vasculaires, neurodégénératives, rénales, ainsi que des infections bactériennes ou virales, de l'agrégation plaquettaire, du cancer, du rejet de greffe ou des lésions pulmonaires. Pour les besoins de la formule (I), A, X, Y, Z, R?1¿, R?2¿ et n sont tels que spécifiés dans la description.

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