Azolyl methyl phenyl derivatives having aromatase inhibitory...

Details Azolyl methyl phenyl derivatives having aromatase inhibitory... Azolyl methyl phenyl derivatives having aromatase inhibitory...

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/41 (2006.01) C07D 233/60 (2006.01) C07D 249/08 (2006.01) C07D 403/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2150326

Compounds exerting excellent aromatase inhibitory activity in vivo and in vitro with higher specificity and greater safety are provided together with the salts thereof. Using the same, there are also provided, prophylactic agents and/or therapeutical agents of estrogen-dependent diseases, contraceptive agents for females, and aromatase inhibitory agents for use in the form of reagents for human or animals. The compounds are of the formula (I), wherein R2 is represented by the formula (II) or (III). Image (I) A: O, S, CH2 D: CH, N R2: Image (II) or Image (III)

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