B-cell depleting agents, like anti-cd20 antibodies or...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2706899

The present invention relates in a first aspect to a B-cell depleting anti- CD20 antibody or a CD20-binding antibody fragment thereof for the treatment of chronic fatigue syndrome and myalgic encephalomyelitis. In particular, the present invention relates to the use of anti-CD20 monoclonal antibodies or fragments thereof which are preferably humanized for the treatment of chronic fatigue syndrome/myalgic encephalomyelitis in a subject afflicted with said disease.

La présente invention concerne en premier lieu un anticorps anti-CD20 de déplétion de cellule B ou un fragment d'anticorps se liant au CD20 pour le traitement du syndrome de fatigue chronique et de l'encéphalomyélite myalgique. En particulier, la présente invention concerne l'utilisation d'anticorps monoclonaux anti-CD20, ou de leurs fragments, adaptés de préférence à l'homme, pour le traitement du syndrome de fatigue chronique et/ou de l'encéphalomyélite myalgique sur un sujet atteint par une telle maladie.

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