B-glucuronidase inhibitor

Details B-glucuronidase inhibitor B-glucuronidase inhibitor

A - Human Necessities

61

K

A61K 31/70 (2006.01) C07H 17/00 (2006.01) A61K 35/78 (1990.01)

Patent

CA 2093442

19 ABSTRACT A inhibitor comprising at least one compound selected from the group consisting of baicalin, oroxylin A-7-0-glucuronide and luteolin-3'-glucuronide; an extract of scutellaria root (baikal skullcap; Scutellariae Radix) and/or schizonepeta spike (Japanese catnip; Schizonepelae Spica); or a Chinese and Japanese traditional prescription comprised of scutellaria root (baikal skullcap; Scu tellariae Radix) and/or schizonepeta spike (Japanese catnip; Schizonepelae Spica) as a crude drug. The .beta.-glucuronidasa inhibitor can relieve the adverse effect, especially diarrhea, caused in the administration of a compound represented by the following formula I Image

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