C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/187, 260/302
C07D 205/085 (2006.01) C07D 401/00 (2006.01) C07D 417/06 (2006.01)
Patent
CA 1340253
.beta.-Lactams having a sulfonic acid substituent in the 1-position and an amine function in the 3-position and having the formula: (see fig. I) wherein R1 is H or acyl derived from a carboxylic acid; R2 is H or alkoxy; R3 and R4, the same or different, are H, alkyl, cycloalkyl, phenyl or substituted phenyl, or one of R3 and R4 is H and the other is alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl; and X is H or SO3X is SO3-M+ wherein M+ is a cation, and the use of said .beta.-lactams as antibiotics.
617057
Cimarusti Christopher Michael
Floyd David Mack
Fritz Alan William
Koster William Henry
Parker William Lawrence
E.r. Squibb & Sons Inc.
Osler Hoskin & Harcourt Llp
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