B1k chain of laminin and methods of use

Details B1k chain of laminin and methods of use B1k chain of laminin and methods of use

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/39 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/78 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2173626

Recombinant laminin B1k and fragments thereof are produced. The recombinant laminin B1k is a subunit of kalinin a basement membrane protein useful for promoting adhesion of keratinocytes to a substrate and treatment of disorders of the dermis.

Selon la présente invention, la chaîne B1k recombinante de laminine ainsi que des fragments de cette chaîne ont été produits. La chaîne B1k recombinante de laminine est une sous-unité de kalinine, une protéine de membrane basale apte à favoriser l'adhésion des kératinocytes à un substrat et permettant de traiter des troubles du derme.

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