G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 15/14 (2006.01)
Patent
CA 2583257
The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7-H1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of B7-H1.
L'invention concerne des procédés de diagnostic par évaluation de l'expression de B7-H1 dans un tissu cancéreux ou un tissu dont on suspecte qu'il est cancéreux, ainsi que des procédés de traitement par le biais d'agents qui interfèrent avec l'interaction du récepteur de B7-H1, et enfin des procédés de sélection de sujets candidats susceptibles de bénéficier d'une immunothérapie anticancéreuse et des procédés d'inhibition de l'expression de B7-H1.
Cheng Lieping
Kwon Eugene D.
Strome Scott E.
Mayo Foundation For Medical Education And Research
Mbm Intellectual Property Law Llp
LandOfFree
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