B7-like polynucleotides, polypeptides, and antibodies

Details B7-like polynucleotides, polypeptides, and antibodies B7-like polynucleotides, polypeptides, and antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 1/18 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 5/00 (2006.01) A61P 5/06 (2006.01) A61P 5/12 (2006.01) A61P 5/14 (2006.01) A61P 5/38 (2006.01) A61P 5/40 (2006.01) A61P 5/48 (2006.01) A61P 7/00 (2006.01) A61P 7/02 (2006.01) A61P 7/04 (2006.01) A61P 7/06 (2006.01) A61P 9/00 (2006.01) A61P 9/02 (2006.01) A

Patent

CA 2406649

The present invention relates to novel human B7-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human B7-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human B7-like polypeptides.

Cette invention a trait à de nouveaux polypeptides humains du type B7 ainsi qu'à des acides nucléiques isolés contenant les régions codantes des gènes codant ces polypeptides. Elle concerne également des vecteurs, des cellules hôtes et des anticorps ainsi que des techniques de recombinaison permettant de produire ces polypeptides du type B7. Elle porte, en outre, sur des méthodes diagnostiques et thérapeutiques des plus utiles en matière de diagnostic et de traitement d'états pathologiques liés à ces nouveaux polypeptides humains du type B7.

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