C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/30 (2006.01) A61K 39/018 (2006.01) C07K 14/44 (2006.01) C07K 16/20 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2058379
ABSTRACT Antigens inducing protective immunity against homologous or heterologous challenge with Babesia bovis which include an antigen which is immunoreactive with a monoclonal antibody recognising a protein located with rhoptries organelles at the apical end of Babesi bovis in infected erythrocytes. Recombinant antigens are also claimed and in particular a recombinant antigen which a component of 21B4 antigen of 313 base pairs and disclosed in FIG 11. Processes for preparation of monoclonal antibody T21B4 as well as processes for preparation of the above antigens are also claimed. Vaccines including the antigens in combination with an appropriate adjuvant are also claimed.
Casu Rosanne E.
Commins Margaret A.
Commonwealth Scientific And Industrial Research Organisation
Mccarthy Tetrault Llp
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