Baccatin derivatives and a process for producing the same

Details Baccatin derivatives and a process for producing the same Baccatin derivatives and a process for producing the same

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2298398

Disclosed are baccatin derivatives of the formulas (I) and (III) Image (wherein R1 and R2 are an OH-protecting group, R3 is aryl or alkyl, R5 is H or alkyl, n is 1-5, Bz is benzoyl and Ac is acetyl) as well as processes for producing the baccatin derivatives by reacting a baccatin of the formula (II) Image with a (.beta.-ketoester in the absence of a catalyst or in the presence of a tin compound or an amine base, preferably under reduced pressure. The baccatin derivatives are useful for producing anti-cancer toxoid compounds.

Affiliated with

Also associated with

Rating

Baccatin derivatives and a process for producing the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Baccatin derivatives and a process for producing the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Baccatin derivatives and a process for producing the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2055964