Backbone-substituted bifunctional dota ligands, complexes...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/08 (2006.01) A61K 31/395 (2006.01) A61K 31/439 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 49/06 (2006.01) A61K 51/00 (2006.01) A61P 35/00 (2006.01) C07D 257/02 (2006.01) C07D 257/10 (2006.01)

Patent

CA 2495442

Backbone-substituted 1,4,7,10-tetraaza cyclododecane-N,N',N'',N''' - tetraacetic acid compounds, metal complexes thereof, compositions thereof, conjugates thereof, and methods of use in diagnostic imaging and treatment of a cellular disorder.

L'invention concerne des composés d'acide 1,4,7,10-tétraazacyclododécane-<i>N,N',N'',N'''</i>-tétraacétique substitués sur le squelette, leurs complexes métalliques, leurs compositions, leurs conjugués, ainsi que leurs méthodes d'utilisation en imagerie diagnostique et dans le traitement de troubles d'origine cellulaire.

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