Bacterial fsh binding inhibitor

Details Bacterial fsh binding inhibitor Bacterial fsh binding inhibitor

A - Human Necessities

61

K

167/113, 195/86

A61K 35/74 (2006.01) C12N 9/52 (2006.01) C12P 1/04 (2006.01) G01N 33/74 (2006.01)

Patent

CA 1287004

ABSTRACT The present invention relates to an FSH-binding inhibitor derived from a microorganism of the genus Serratia characterized by the following features: a molecular weight of over 6000; inactivation by heating at 60°C for 30 minutes; inactivation by pH below 4; insolubility in ether, 75% acetone and 40% ammonium sulfate; solubility in 80% ethanol; and absence of serine protease activity. The FSH-binding inhibitor of the present invention has use as a reagent in the study of FSH-receptor interactions and in purification of the FSH receptor.

489800

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