A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/74 (2006.01) A61K 39/00 (2006.01) A61K 39/155 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)
Patent
CA 2367917
The invention concerns the use of a membrane fraction of gram-negative bacteria, in particular Klebsiella pneumoniae combined with an antigen or hapten for preparing a pharmaceutical composition designed to direct the immune response towards a Th1 and/or a mixed Th1/Th2 type response directed against said antigen or hapten. The invention further concerns methods for preparing said membrane fractions and pharmaceutical compositions containing them and their uses for preventing and treating infectious diseases, in particular those involving paramyxovirus such as VRS, and cancers, in particular those with tumour-associated antigens.
La présente invention concerne l'utilisation d'une fraction membranaire de bactéries à gram négatif, notamment de Klebsiella pneumoniae, associée à un antigène ou haptène pour la préparation d'une composition pharmaceutique destinée à orienter la réponse immunitaire vers une réponse de type Th1 et/ou de type mixte Th1/Th2 dirigée contre ledit antigène ou haptène. L'invention comprend en outre des procédés de préparation desdites fractions membranaires et les compositions pharmaceutiques les contenant et leurs applications à la prévention et le traitement de maladies infectieuses, en particulier les infections à paramyxovirus telles que le VRS, et les cancers, notamment ceux dont les tumeurs sont associées à des antigènes tumoraux.
Beck Alain
Bonnefoy Jean-Yves
Corvaia Nathalie
Libon Christine
N'guyen Thien Ngoc
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Pierre Fabre Medicament
LandOfFree
Bacterial membrane fractions with adjuvant effect does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bacterial membrane fractions with adjuvant effect, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bacterial membrane fractions with adjuvant effect will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1408091