Bacterial vaccines with cell wall-associated ceramide-like...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) A61K 39/02 (2006.01) A61K 39/04 (2006.01) C07H 15/04 (2006.01)

Patent

CA 2748819

The invention is directed compositions and methods related to bacterial cells physically associated with ceramide-like glycolipids. The invention allows for delivery of ceramide-like glycolipid adjuvants directly to the same cells that become infected with a bacterial vaccine. The compositions and methods of the present invention are useful for the prevention and treatment of diseases.

L'invention concerne des compositions et des procédés concernant des cellules bactériennes physiquement associées à des glycolipides du type céramide. L'invention permet l'administration d'adjuvants glycolipidiques du type céramide directement vers les cellules qui deviennent infectées par un vaccin bactérien. Les compositions et les procédés de la présente invention sont utiles pour la prévention et le traitement de maladies.

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