Bacterial virulence factors and uses thereof

Details Bacterial virulence factors and uses thereof Bacterial virulence factors and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 35/74 (2006.01) A61K 38/16 (2006.01) A61K 39/02 (2006.01) A61K 39/108 (2006.01) A61P 31/00 (2006.01) C07K 14/24 (2006.01) C12N 1/20 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2543763

The invention relates to, in part, secreted proteins of bacterial pathogens and methods for their use. More specifically, the invention provides in part several new common secreted proteins for A/E pathogens. In some embodiments of the invention, these polypeptides and nucleic acid molecules encoding these polypeptides, or portions thereof, are useful as vaccines, diagnostics, or drug screening tools for A/E pathogenic infections, or as reagents.

L'invention concerne dans une certaine mesure des protéines sécrétées d'agents pathogène s bactériens et leurs méthodes d'utilisation. Plus précisément, cette invention concerne pour partie plusieurs nouvelles protéine communes sécrétées pour agents pathogènes A/E. Dans certains modes de réalisation, ces polypeptides et les molécules d'acides nucléiques codant pour ces polypeptides, en tout ou en partie, conviennent comme vaccins, agents diagnostiques ou comme outils de criblage de médicaments pour infections pathogènes A/E, ou comme réactifs.

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