Bactericidal formulations for use in the area of veterinary...

A - Human Necessities – 61 – K

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167/223, 167/225

A61K 31/47 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01)

Patent

CA 1273579

Bactericidal formulations for use in the area of veterinary medicine A B S T R A C T A method of treating livestock infected with, or protecting livestock against infection from, barcteria which comprises administering to such livestock an antibacterially effective amount of a quinolonecarboxylic acid or derivative of the formula Image in which A represents nitrogen or =C-R4, R4 represents hydrogen, fluorine, chlorine, nitro or methyl, 8 represents Image , and 8 also, represents Image when R1 does not denote cyclo- propyl, and R5 represents hydrogen, a branched or unbranched alkyl group which has 1 to 4 carbon atoms and which can optionally be substituted by a hydroxyl or methoxy group, R6 represents hydrogen, methyl or phenyl, Le A 23 872 R7 represents hydrogen or methyl, R represents amino, alkyl- or dialkylamino having 1 or 2 carbon atoms in the alkyl group, aminomethyl, alkyl- or dialkylaminomethyl having 1 or 2 carbon atoms in the alkyl group, R1 represents an alkyl radical having 1 to 3 carbon atoms, cyclopropyl, 2-fluoroethyl vinyl, methoxy, 4-fluorophenyl or methylamino R2 represents hydrogen, alkyl having 1 to 6 carbon atoms, and cyclohexyl, benzyl, 2-oxo- propyl, phenacyl and ethoxycarbonylmethyl, R3 represents hydrogen, methyl or ethyl, Z represents oxygen, nitrogen which is substi- tuted by methyl or phenyl, and =CH2-, or a pharmaceutically utilizable salt thereof. Le A 23 872

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