Bacteriocins from streptococcus thermophilus

Details Bacteriocins from streptococcus thermophilus Bacteriocins from streptococcus thermophilus

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A23B 4/20 (2006.01) A23C 9/123 (2006.01) A23C 9/127 (2006.01) A23C 19/032 (2006.01) A23C 19/11 (2006.01) A23L 3/3571 (2006.01) A61K 8/64 (2006.01) A61K 38/16 (2006.01) C07K 14/315 (2006.01) C12N 1/20 (2006.01) C12N 15/31 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2148223

The invention relates to two new Steptococcus thermophilus bacteriocins having the amino acid sequences SEQ ID NO:1 and SEQ ID NO:2, the signal peptides of these two bacteriocins, the nucleotide sequences encoding these bacteriocins especially an operon encoding the said bacteriocins having the sequence SEQ ID NO:3, the strains producing at least one of these bacteriocins especially the strain CNCM I-1351, a method for producing a supernatant extract comprising at least one of these two bacteriocins, and use of these bacteriocins in the preparation of food products, especially cheeses and acidified milks, and cosmetic products as active agent against pathogens.

L'invention porte sur deux nouvelles bactériocines du Streptococcus thermophilus comportant les séquences d'acides aminés SEQ ID N DEG :1 et SEQ ID N DEG :2, les peptides signaux de ces deux bactériocines, les séquences nucléotidiques pour ces bactériocines et un particulier un opéron codant lesdites bactériocines ayant la séquence SEQ ID N DEG :3, les souches produisant au moins l'une de ces bactériocines et en particulier la souche CNCM I-1351, un procédé d'obtention d'un extrait surnageant comportant au moins l'une de ces deux bactériocines, et l'utilisation de ces bactériocines dans la préparation de produits alimentaires et notamment de fromages et laits acidifiés, et de cosmétiques à activité antipathogène.

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