C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/14 (2006.01) A61K 38/46 (2006.01) C07K 14/01 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2474145
A nucleic acid comprising a nucleotide sequence encoding a lysin, which nucleotide sequence comprises the sequence shown in SEQ IDNo. 1 or a variant, homologue or derivative thereof. A novel lysin obtainable from a bacteriophage capable of colonising Clostridium perfringens, and the use thereof as a medicament for the treatment of a disorder associated with pathogenic Clostridium bacteria, for example.
L'invention concerne un acide nucléique comprenant une séquence d'acides nucléiques codant pour une lysine. Cette séquence d'acides nucléiques comprend la séquence indiquée dans SEQ IDNo. 1, ou une variante, une séquence homologue ou dérivée de celle-ci. L'invention concerne une nouvelle lysine pouvant être obtenue à partir d'un bactériophage capable de coloniser Clostridium perfringens, ainsi que son utilisation en tant que médicament pour le traitement d'un trouble associé à la bactérie pathogène Clostridium, par exemple.
Loessner Martin
Morgan Andrew John
Zimmer Markus
Biomerieux S.a.
Borden Ladner Gervais Llp
Hyglos Invest Gmbh
Profos Ag
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