Bacteriophage preparation and use

Details Bacteriophage preparation and use Bacteriophage preparation and use

A - Human Necessities

01

N

A01N 63/00 (2006.01) A61K 35/76 (2006.01) A61K 39/42 (2006.01) A61L 2/00 (2006.01) A61L 2/025 (2006.01) A61L 2/18 (2006.01)

Patent

CA 2740010

The invention relates to a bacteriophage preparation having at least one bacteriophage in alkaline buffer solution, said bacteriophage being specifically effective against at least one bacterial strain, in combination with at least one surface-active agent that is preferably a polyhexamethyl biguanide (polyhexanide) stabilized in an alkaline range between pH 7.5 and pH 9Ø The invention further relates to the use of such a bacteriophage preparation for the production of a pharmaceutical, particularly for therapeutic, preventative, and disinfecting antibacterial use. Finally, the invention also relates to a disinfection method using the bacteriophage preparation together with low-frequency ultrasound.

L'invention concerne une préparation bactériophage comprenant au moins un bactériophage agissant spécifiquement à l'encontre d'une souche bactérienne dans une solution tampon alcaline en association avec au moins un agent tensioactif, qui est, de préférence, un polyhexaméthylbiguanide (polyhexanide) stabilisé dans une plage de pH alcalin comprise entre 7,5 et 9. L'invention concerne, de plus, l'utilisation d'une préparation bactériophage de ce type dans la production d'un médicament s'utilisant de préférence à des fins thérapeutiques, prophylactiques, désinfectantes, et antibactériennes. Enfin, l'invention concerne une méthode de désinfection par utilisation de la préparation bactériophage avec des ultrasons basse fréquence.

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