Baculovirus expression vectors

C - Chemistry – Metallurgy – 12 – N

Patent

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195/1.2

C12N 15/79 (2006.01) C12N 15/68 (2006.01) C12N 15/866 (2006.01)

Patent

CA 2033070

-45- ABSTRACT OF THE DISCLOSURE A method and composition for improving the level of expression of a gene or collection of genes by providing a novel baculovirus promoter to which a heterologous gene is attached. The novel promoter may contain a modification of a natural viral promoter or may be totally synthetic. The novel baculovirus promoter may also comprise a combination promoter such as a promoter with a double start site or a combination of two different promoters. Foreign gene placement in a novel location or genomic orientation is also included.

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